T Chadwick | PHSI-BRG

ALternatives To prophylactic Antibiotics for the treatment of Recurrent urinary tract infection in women (ALTAR): Study protocol for a multicentre, pragmatic, patient-randomised, non-inferiority trial

Trials 2018; 19:616

Forbes R, Ali A, Abouhajar A, Brennand C, Brown H, Carnell S, Chadwick T, Eardley I, Lecouturier J, Mossop H, Pearce I, Pickard R, Thiruchelvam N, Walton K, Wilkinson J, Harding C

DOI

Continuous low-dose antibiotic prophylaxis for adults with repeated urinary tract infections (AnTIC): A randomised, open-label trial

Lancet Infectious Diseases 2018; 18(9):957-968

Fisher H, Oluboyede Y, Chadwick T, Abdel-Fattah M, Brennand C, Fader M, Harrison S, Hilton P, Larcombe J, Little P, McClurg D, McColl E, N’Dow J, Ternent L, Thiruchelvam N, Timoney A, Vale L, Walton K, von Wilamowitz-Moellendorff A, Wilkinson J, Wood R, Pickard R

DOI

Randomised controlled trial of GM-CSF in critically ill patients with impaired neutrophil phagocytosis

Thorax 2018; 73(10):918-925

Pinder EM, Rostron AJ, Hellyer TP, Ruchaud-Sparagano M-H, Scott J, Macfarlane JG, Wiscombe S, Widdrington JD, Roy AI, Linnett VC, Baudouin SV, Wright SE, Chadwick T, Fouweather T, Juss JK, Chilvers ER, Bowett SA, Parker J, McAuley DF, Conway Morris A, Simpson AJ

DOI

Continuous low-dose antibiotic prophylaxis to prevent urinary tract infection in adults who perform clean intermittent self-catheterisation: The AnTIC RCT

Health Technology Assessment 2018; 22(24)

Pickard R, Chadwick T, Oluboyede Y, Brennand C, von Wilamowitz-Moellendorff A, McClurg D, Wilkinson J, Ternent L, Fisher H, Walton K, McColl E, Vale L, Wood R, Abdel-Fattah M, Hilton P, Fader M, Harrison S, Larcombe J, Little P, Timoney A, N’Dow J, Armstrong H, Morris N, Walker K, Thiruchelvam N

DOI

Intensive versus standard physical rehabilitation therapy in the critically ill (EPICC): A multicentre, parallel-group, randomised controlled trial

Thorax 2018; 73(3):213-221

Wright SE, Thomas K, Watson G, Baker C, Bryant A, Chadwick TJ, Shen J, Wood R, Wilkinson J, Mansfield L, Stafford V, Wade C, Furneval J, Henderson A, Hugill K, Howard P, Roy A, Bonner S, Baudouin S

DOI

Autologous tolerogenic dendritic cells for rheumatoid and inflammatory arthritis

Annals of the Rheumatic Diseases 2017; 76:227-234

Bell GM, Anderson AE, Diboll J, Reece R, Eltherington O, Harry RA, Fouweather T, MacDonald C, Chadwick T, McColl E, Dunn J, Dickinson AM, Hilkens CMU, Isaacs JD

DOI

Does efavirenz replacement improve neurological function in treated HIV infection?

HIV Medicine 2017; 18(9):690-695

Payne B, Chadwick TJ, Blamire A, Anderson KN, Parikh J, Qian J, Hynes AM, Wilkinson J, Price DA

DOI

An observational study of donor ex vivo lung perfusion in UK lung transplantation: DEVELOP-UK

Health Technology Assessment 2016; 20(85)

Fisher A, Andreasson A, Chrysos A, Lally J, Mamasoula V, Exley C, Wilkinson J, Qian J, Watson G, Lewington O, Chadwick T, McColl E, Pearce M, Mann K

DOI

Antibiotic treatment for intermittent bladder catheterisation with once daily prophylaxis (the AnTIC study): Study protocol for a randomised controlled trial

Trials 2016; 17:276

Brennand C, von Wilamowitz-Moellendorff A, Dunn S, Wilkinson J, Chadwick T, Ternent L, Oluboyede Y, Wood R, Walton K, Fader M, N’Dow J, Abdel-Fattah M, McClurg D, Little P, Hilton P, Timoney A, Morris N, Thiruchelvam N, Larcombe J, Harrison S, Armstrong H, McColl E, Pickard R

DOI

Neurocognitive and neurometabolic effects of switch from efavirenz to ritonavir-boosted lopinavir

HIV Medicine 2016; 17(S1):14-71

Payne B, Chadwick T, Blamire A, Qian J, Hynes AM, Wilkinson J, Price DA, Anderson K

DOI

Randomised controlled trial of granulocyte macrophage colony stimulating factor in critically ill patients with impaired neutrophil function

American Journal of Respiratory and Critical Care Medicine 2016; 201:A2727

Pinder EM, Rostron AJ, Hellyer TP, Ruchaud-Sparagano M-H, Scott J, Macfarlane JG, Wiscombe S, Widdrington JD, Allen T, Roy AI, Linnett VC, Baudouin SV, Wright SE, Chadwick T, Fouweather A, Bowett S, Parker J, Corris PA, McAuley DF, Morris AC, Simpson AJ

Cardiac Iodine-123-Meta-Iodo-Benzylguanidine uptake in carotid sinus hypersensitivity

PLoS ONE 2015; 10(6):e0126241

Tan MP, Murray A, Hawkins T, Chadwick TJ, Kerr SRJ, Parry SW

DOI

Extra Physiotherapy in Critical Care (EPICC) trial protocol: A randomised controlled trial of intensive versus standard physical rehabilitation therapy in the critically ill

BMJ Open 2015; 5(5):e008035

Thomas K, Wright SE, Watson G, Baker C, Stafford V, Wade C, Chadwick TJ, Mansfield L, Wilkinson J, Shen J, Deverill M, Bonner S, Hugill K, Howard P, Henderson A, Roy A, Furneval J, Baudouin SV

DOI

Response to comment on Little et al. Recovery of hypoglycemia awareness in long-standing type 1 diabetes: A multicenter 2 × 2 factorial randomized controlled trial comparing insulin pump with multiple daily injections and continuous with conventional glucose self-monitoring (HypoCOMPaSS). Diabetes Care 2014;37:2114-2122

Diabetes Care 2014; 37(12):e272-e273

Little SA, Leelarathna L, Walkinshaw E, Tan HK, Chapple O, Lubina-Solomon A, Chadwick TJ, Barendse S, Stocken DD, Brennand C, Marshall SM, Wood R, Speight J, Kerr D, Flanagan D, Heller SR, Evans ML, Shaw JAM

DOI

Symptomatic presentation of carotid sinus hypersensitivity is associated with impaired cerebral autoregulation

Journal of the American Heart Association 2014; 3(3):e000514

Tan MP, Chadwick TJ, Kerr SRJ, Parry SW

DOI

Recovery of hypoglycemia awareness in long-standing type 1 diabetes: A multicenter 2 x 2 factorial randomized controlled trial comparing insulin pump with multiple daily injections and continuous with conventional glucose self-monitoring (HypoCOMPaSS)

Diabetes Care 2014; 37(8):2114-2122

Little SA, Leelarathna L, Walkinshaw E, Tan HK, Chapple O, Lubina-Solomon A, Chadwick TJ, Barendse S, Stocken DD, Brennand C, Marshall SM, Wood R, Speight J, Kerr D, Flanagan D, Heller SR, Evans ML, Shaw JAM

DOI

Restoration of self-awareness of hypoglycemia in adults with long-standing type 1 diabetes

Diabetes Care 2013; 36(12):4063-4070

Leelarathna L, Little SA, Walkinshaw E, Tan HK, Lubina-Solomon A, Kumareswaran K, Lane AP, Chadwick T, Marshall SM, Speight J, Flanagan D, Heller SR, Shaw JAM, Evans ML

DOI

Are social inequalities widening in generalised and abdominal obesity and overweight among English adults?

PLoS ONE 2013; 8(11):e79027

Howel D, Stamp E, Chadwick TJ, Adamson AJ, White M

DOI

Vitamin D supplementation in older people (VDOP): Study protocol for a randomised controlled intervention trial with monthly oral dosing with 12,000 IU, 24,000 IU or 48,000 IU of vitamin D3

Trials 2013; 14:299

Schoenmakers I, Francis RM, McColl E, Chadwick T, Goldberg GR, Harle C, Yarnall A, Wilkinson J, Parker J, Prentice A, Aspray T

DOI

Comparison of Optimised MDI versus Pumps with or without Sensors in Severe Hypoglycaemia (the Hypo COMPaSS trial)

BMC Endocrine Disorders 2012; 12:33

Little S, Chadwick T, Choudhary P, Brennand C, Stickland J, Barendse S, Olateju T, Leelarathna L, Walkinshaw E, Tan HK, Marshall SM, Thomas RM, Heller S, Evans M, Kerr D, Flanagan D, Speight J, Shaw JAM

DOI

Carotid sinus hypersensitivity: Disease state or clinical sign of ageing? Insights from a controlled study of autonomic function in symptomatic and asymptomatic subjects

EP Europace 2010; 12(11):1630-1636

Tan MP, Kenny RAM, Chadwick TJ, Kerr SRJ, Parry SW

DOI

Home orthostatic training in vasovagal syncope modifies autonomic tone: Results of a randomized, placebo-controlled pilot study

EP Europace 2010; 12(2):240-246

Tan MP, Newton JL, Chadwick TJ, Gray JC, Nath S, Parry SW

DOI

Results of carotid sinus massage in a tertiary referral unit—is carotid sinus syndrome still relevant?

Age and Ageing 2009; 38(6):680-686

Tan MP, Newton JL, Reeve P, Murray A, Chadwick TJ, Parry SW

DOI

Laryngopharyngeal reflux: A prospective analysis of a 34 item symptom questionnaire

Clinical Otolaryngology 2009; 34(5):455-459

Papakonstantinou L, Leslie P, Gray J, Chadwick T, Hudson M, Wilson JA

DOI

The intravenous adenosine test: A new test for the identification of bradycardia pacing indications? A pilot study in subjects with bradycardia pacing indications, vasovagal syncope and controls

QJM: An International Journal of Medicine 2009; 102(7):461–468

Parry SW, Chadwick T, Gray JC, Bexton RS, Tynan M, Bourke JP, Nath S

DOI

Bayesian model comparison and model averaging for small-area estimation

Annals of Applied Statistics 2009; 3(1):199-221

Aitkin M, Liu CC, Chadwick T

DOI

Maternal exposure to ambient air pollutants and risk of congenital anomalies

Environmental Research 2009; 109(2):181-187

Rankin J, Chadwick T, Natarajan M, Howel D, Pearce MS, Pless-Mulloli T

DOI

Localization of angiogenic growth factors and their receptors in the human placental bed throughout normal human pregnancy

Placenta 2009; 30(1):79-87

Schiessl B, Innes BA, Bulmer JN, Otun HA, Chadwick TJ, Robson SC, Lash GE

DOI

The relationship between carotid sinus hypersensitivity, orthostatic hypotension, and vasovagal syncope: A case–control study

EP Europace 2008; 10(12):1400–1405

Tan MP, Newton JL, Chadwick TJ, Parry SW

DOI

Changes in baroreflex sensitivity with home orthostatic training in vasovagal syncope - A randomized, placebo controlled pilot study

Hypertension 2008; 52(4):747-775

Tan MP, Newton JL, Chadwick T, Parry SW

DOI

Does living near heavy industry cause lung cancer in women? A case-control study using life grid interviews

Thorax 2006; 61(12):1076-1082

Edwards R, Pless-Mulloli T, Howel D, Chadwick T, Bhopal R, Harrison R, Gribbin H

DOI

Randomised controlled trial of welfare rights advice accessed via primary health care: Pilot study [ISRCTN61522618]

BMC Public Health 2006; 6:162

Mackintosh J, White M, Howel D, Chadwick T, Moffatt S, Deverill M, Sandell A

DOI

Bayesian point null hypothesis testing via the posterior likelihood ratio

Statistics and Computing 2005; 15(3):217-230

Aitkin M, Boys RJ, Chadwick T

DOI

Thomas Chadwick

Senior Biostatistician

Population Health Sciences Institute

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