Theophile Bigirumurame

Theophile Bigirumurame

Research Associate

Population Health Sciences Institute

Biography

Background

Theo worked in the Biostatistics Research Group from August 2017 until June 2024. He now works in Astrellas as a Statistical Manager.

Publications

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Svetlana Cherlin, Theophile Bigirumurame, Michael J Grayling, Jérémie Nsengimana, Luke Ouma, Aida Santaolalla, Fang Wan, S Faye Williamson, James MS Wason (2023). Utilising high-dimensional data in randomised clinical trials: A review of methods and practice. Research Methods in Medicine & Health Sciences.

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Vicky Brocklebank, Patrick R. Walsh, Kate Smith-Jackson, Thomas M. Hallam, Kevin J. Marchbank, Valerie Wilson, Theophile Bigirumurame, Tina Dutt, Emma K. Montgomery, Michal Malina, Edwin K. S. Wong, Sally Johnson, Neil S. Sheerin, David Kavanagh (2023). Atypical hemolytic uremic syndrome in the era of terminal complement inhibition: an observational cohort study. Blood.

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Theophile Bigirumurame, Shaun Kuan Wei Hiu, M Dawn Teare, James M S Wason, Andrew Bryant, Matthew Breckons (2023). Current practices in studies applying the target trial emulation framework: a protocol for a systematic review. BMJ Open.

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Alaa Abouhajar, Lisa Alcock, Theophile Bigirumurame, Penny Bradley, Laura Brown, Ian Campbell, Silvia Del Din, Julie Faitg, Gavin Falkous, Gráinne S. Gorman, Rachel Lakey, Robert McFarland, Jane Newman, Lynn Rochester, Vicky Ryan, Hesther Smith, Alison Steel, Renae J. Stefanetti, Huizhong Su, Robert W. Taylor, Naomi J. P. Thomas, Helen Tuppen, Amy E. Vincent, Charlotte Warren, Gillian Watson (2022). Acipimox in Mitochondrial Myopathy (AIMM): study protocol for a randomised, double-blinded, placebo-controlled, adaptive design trial of the efficacy of acipimox in adult patients with mitochondrial myopathy. Trials.

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Giang Nguyen, Louise Hayes, Lem Ngongalah, Theophile Bigirumurame, Laura Gaudet, Adefisayo Odeniyi, Angela Flynn, Lisa Crowe, Becky Skidmore, Alexandre Simon, Vikki Smith, Nicola Heslehurst (2022). Association between maternal adiposity measures and infant health outcomes: A systematic review and meta-analysis. Obesity Reviews.

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Grayling MJ, Bigirumurame T, Cherlin S, Ouma L, Zheng H, Wason J (2021). Innovative trial approaches in immune-mediated inflammatory diseases: Current use and future potential. BMC Rheumatol 2021; 5:21.

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Slight SP, Tolley CL, Bates DW, Fraser R, Bigirumurame T, Kasim A, Balaskonis K, Narrie S, Heed A, Orav EJ, Watson NW (2019). Medication errors and adverse drug events in a UK hospital during the optimisation of electronic prescriptions: A prospective observational study. Lancet Digital Health 2019; 1:e403-12.

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Jameson SS, Asaad A, Diament M, Kasim A, Bigirumurame T, Baker P, Mason J, Partington P, Reed M (2019). Antibiotic-loaded bone cement is associated with a lower risk of revision following primary cemented total knee arthroplasty. Bone Joint J 2019; 101-B:1331-47.

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Dyson JK, Wong LL, Bigirumurame T, Hirschfield GM, Kendrick S, Oo YH, Lohse AW, Heneghan MA, Jones DEJ, UK-AIH Consortium (2018). Inequity of care provision and outcome disparity in autoimmune hepatitis in the United Kingdom. Aliment Pharm Ther 2018; 48:951-60.

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Bigirumurame T, Kasim AS (2017). Can testing clinical significance reduce false positive rates in randomized controlled trials? A snap review. BMC Res Notes 2017; 10:775.

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Louis E, Adriaensens P, Guedens W, Bigirumurame T, Baeten K, Vanhove K, Vandeurzen K, Darquennes K, Vansteenkiste J, Dooms C, Shkedy Z, Mesotten L, Thomeer M (2016). Detection of lung cancer through metabolic changes measured in blood plasma. J Thorac Oncol 2016; 11:516-23.

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Verbist B, Klambauer G, Vervoort L, Talloen W, Shkedy Z, Thas O, Bender A, Göhlmann HWH, Hochreiter S (2015). Using transcriptomics to guide lead optimization in drug discovery projects: Lessons learned from the QSTAR project. Drug Discov Today 2015; 20:505-13.

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