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Theophile Bigirumurame
Andy Bryant
Thomas Chadwick
Svetlana Cherlin
Mike Cole
Holly Fisher
Tony Fouweather
Michael Grayling
Shaun Hiu
Valentina Mamasoula
John Matthews
Helen Mossop
Jérémie Nsengimana
Vicky Ryan
Dawn Teare
James Wason
Faye Williamson
Nina Wilson
Haiyan Zheng
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Ruqayya Azher
Aritra Mukherjee
Luke Ouma
Samuel Sarkodie
Lou Whitehead
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Mike Cole
Biostatistician
Population Health Sciences Institute
Contact
Email:
michael.cole@ncl.ac.uk
Telephone:
+44 (0) 191 208 4587
Address:
Population Health Sciences Institute
,
Baddiley-Clark Building
, Richardson Road, Newcastle upon Tyne NE2 4AX, UK
Publications
You can quickly discover relevant content by members of the PHSI-BRG by filtering publications
here
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Adjuvant rituximab, a potential treatment for the young patient with Graves' hyperthyroidism (RiGD): Study protocol for a single-arm, single-stage, phase II trial
BMJ Open
2019; 9(1):e024705
Cole M
,
Hynes AM
,
Howel D
,
Hall L
,
Abinun M
,
Allahabadia A
,
Barrett T
,
Boelaert K
,
Drake AJ
,
Dimitri P
,
Kirk J
,
Zammitt N
,
Pearce S
,
Cheetham T
DOI
Drooling Reduction Intervention randomised trial (DRI): Comparing the efficacy and acceptability of hyoscine patches and glycopyrronium liquid on drooling in children with neurodisability
Archives of Disease in Childhood
2018; 103(4):371-376
Parr JR
,
Todhunter E
,
Pennington L
,
Stocken D
,
Cadwgan J
,
O’Hare AE
,
Tuffrey C
,
Williams J
,
Cole M
,
Colver AF
DOI
A feasibility study incorporating a pilot randomised controlled trial of oral feeding plus pre-treatment gastrostomy tube versus oral feeding plus as-needed nasogastric tube feeding in patients undergoing chemoradiation for head and neck cancer (TUBE trial): Study protocol
Pilot and Feasibility Studies
2016; 2:29
Paleri V
,
Wood J
,
Patterson J
,
Stocken DD
,
Cole M
,
Vale L
,
Franks J
,
Guerrero-Urbano T
,
Donnelly R
,
Barclay S
,
Rapley T
,
Rousseau N
DOI
PARP1 expression, activity and ex vivo sensitivity to the PARP inhibitor, talazoparib (BMN 673), in chronic lymphocytic leukaemia
Oncotarget
2015; 6(41):43978-43991
Herriott A
,
Tudhope SJ
,
Junge G
,
Rodrigues N
,
Patterson MJ
,
Woodhouse L
,
Lunec J
,
Hunter JE
,
Mulligan EA
,
Cole M
,
Allinson LM
,
Wallis JP
,
Marshall S
,
Wang E
,
Curtin NJ
,
Willmore E
DOI
Abstract 5457: Cytarabine leaves a mutational fingerprint in relapsing leukemia
Cancer Research
2014; 74(Suppl 19):5457
Fordham SE
,
Cole M
,
Irving JA
,
Allan JM
DOI
Cytarabine preferentially induces mutation at specific sequences in the genome which are identifiable in relapsed acute myeloid leukaemia
Leukemia
2015; 29(2):491-494
Fordham SE
,
Cole M
,
Irving JA
,
Allan JM
DOI
Hepatocellular cancer: The impact of obesity, type 2 diabetes and a multidisciplinary team
Journal of Hepatology
2014; 60(1):110-117
Dyson J
,
Jaques B
,
Chattopadyhay D
,
Lochan R
,
Graham J
,
Das D
,
Aslam T
,
Patanwala I
,
Gaggar S
,
Cole M
,
Sumpter K
,
Stewart S
,
Rose J
,
Hudson M
,
Manas D
,
Reeves HL
DOI
Adaptive dosing approaches to the individualization of 13-cis-retinoic acid (isotretinoin) treatment for children with high-risk neuroblastoma
Clinical Cancer Research
2013; 19(2):469-479
Veal GJ
,
Errington J
,
Rowbotham SE
,
Illingworth NA
,
Malik G
,
Cole M
,
Daly AK
,
Pearson ADJ
,
Boddy AV
DOI
MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma
Acta Neuropathologica
2012; 123(4):501-513
Ryan SL
,
Schwalbe EC
,
Cole M
,
Lu Y
,
Lusher ME
,
Megahed H
,
O’Toole K
,
Nicholson SL
,
Bognar L
,
Garami M
,
Hauser P
,
Korshunov A
,
Pfister SM
,
Williamson D
,
Taylor RE
,
Ellison DW
,
Bailey S
,
Clifford SC
DOI
Pharmacokinetics of high-dose cyclophosphamide and its metabolites in paediatric patients
Pediatric Blood & Cancer
2011; 57(5):705-897
Chinnaswamy G
,
Errington J
,
Foot A
,
Boddy AV
,
Veal GJ
,
Cole M
DOI
Pharmacokinetics of cyclophosphamide and its metabolites in paediatric patients receiving high-dose myeloablative therapy
European Journal of Cancer
2011; 47(10):1556-1563
Chinnaswamy G
,
Errington J
,
Foot A
,
Boddy AV
,
Veal GJ
,
Cole M
DOI
Poly(ADP-ribose) polymerase-1 (PARP-1) pharmacogenetics, activity and expression analysis in cancer patients and healthy volunteers
Biochem J
2011; 436(3):671-679
Zaremba T
,
Thomas HD
,
Cole M
,
Coulthard SA
,
Plummer ER
,
Curtin NJ
DOI
TP53 mutations in favorable-risk wnt/wingless-subtype medulloblastomas
Journal of Clinical Oncology
2011; 29(12):e344-e346
Lindsey JC
,
Hill RM
,
Megahed H
,
Lusher ME
,
Schwalbe EC
,
Cole M
,
Hogg TL
,
Gilbertson RJ
,
Ellison DW
,
Bailey S
,
Clifford SC
DOI
Rapid diagnosis of medulloblastoma molecular subgroups
Clinical Cancer Research
2011; 17(7):1883-1894
Schwalbe EC
,
Lindsey JC
,
Straughton D
,
Hogg TL
,
Cole M
,
Megahed H
,
Ryan SL
,
Lusher ME
,
Taylor MD
,
Gilbertson RJ
,
Ellison DW
,
Bailey S
,
Clifford SC
DOI
Percentage tumor necrosis following chemotherapy in neuroblastoma correlates with MYCN status but not survival
Pediatric Hematology and Oncology
2011; 28(2):106-114
Bomken S
,
Davies B
,
Chong L
,
Cole M
,
Wood KM
,
McDermott M
,
Tweddle DA
DOI
Doxorubicin-induced suppression of poly(ADP-ribose) polymerase-1 (PARP-1) activity and expression and its implication for PARP inhibitors in clinical trials
Cancer Chemotherapy and Pharmacology
2010; 66(4):807-812
Zaremba T
,
Thomas H
,
Cole M
,
Plummer ER
,
Curtin NJ
DOI
Glomerular toxicity persists 10 years after ifosfamide treatment in childhood and is not predictable by age or dose
Pediatric Blood & Cancer
2010; 54(7):983-989
Skinner R
,
Parry A
,
Price L
,
Cole M
,
Craft AW
,
Pearson ADJ
DOI
Malnourished Malawian patients presenting with large Wilms tumours have a decreased vincristine clearance rate
European Journal of Cancer
2010; 46(10):1841-1847
Israels T
,
Damen CWN
,
Cole M
,
van Geloven N
,
Boddy AV
,
Caron HN
,
Beijnen JH
,
Molyneux EM
,
Veal GJ
DOI
Influence of pharmacogenetics on response and toxicity in breast cancer patients treated with doxorubicin and cyclophosphamide
British Journal of Cancer
2010; 102(6):1003-1009
Bray J
,
Sludden J
,
Griffin MJ
,
Cole M
,
Verrill M
,
Jamieson D
,
Boddy AV
DOI
High Frequency of p53/MDM2/p14ARF pathway abnormalities in relapsed neuroblastoma
Clinical Cancer Research
2010; 16(4):1108–1118
Carr-Wilkinson J
,
O’Toole K
,
Wood KM
,
Challen CC
,
Baker AG
,
Board JR
,
Evans L
,
Cole M
,
Cheung N-KV
,
Boos J
,
Köhler G
,
Leuschner I
,
Pearson ADJ
,
Lunec J
,
Tweddle DA
DOI
Persistent nephrotoxicity during 10-year follow-up after cisplatin or carboplatin treatment in childhood: Relevance of age and dose as risk factors
European Journal of Cancer
2009; 45(18):3213-3219
Skinner R
,
Parry A
,
Price L
,
Cole M
,
Craft AW
,
Pearson ADJ
DOI
Screening infants for neuroblastoma: The parents' perspective
Pediatric Hematology and Oncology
1994; 11(4):433-437
Bell S
,
Parker L
,
Cole M
,
Craft AW
DOI
Poly(ADP-ribose) polymerase-1 polymorphisms, expression and activity in selected human tumour cell lines
British Journal of Cancer
2009; 101(2):256-262
Zaremba T
,
Ketzer P
,
Cole M
,
Coulthard S
,
Plummer ER
,
Curtin NJ
DOI
Human renal function maturation: A quantitative description using weight and postmenstrual age
Pediatric Nephrology
2009; 24(1):67-76
Rhodin MM
,
Anderson BJ
,
Peters AM
,
Coulthard MG
,
Wilkins B
,
Cole M
,
Chatelut E
,
Grubb A
,
Veal GJ
,
Keir MJ
,
Holford NHG
DOI
Estimation of renal function and its potential impact on carboplatin dosing in children with cancer
British Journal of Cancer
2008; 99(6):894-899
Chinnaswamy G
,
Cole M
,
Boddy AV
,
Keir M
,
Price L
,
Parry A
,
English M
,
Veal GJ
DOI
Mismatch repair defects in childhood acutelymphoblastic leukaemia at diagnosis and relapse
British Journal of Haematology
2008; 141(S1):1-121
Matheson EC
,
Cole M
,
Wilkinswand BS
,
Hall AG
DOI
Pharmacogenetics and metabolism of cyclophosphamidein paediatric cancer patients
Pediatric Blood & Cancer
2007; 49(4):398-605
Chinnaswamv G
,
Veal GJ
,
Cole M
,
Taylor GA
,
Errington JE
,
Gerrard M
,
Boddy AV
DOI
p53 is nuclear and functional in both undifferentiated and differentiated neuroblastoma
Cell Cycle
2007; 6(21):2685-2696
Chen L
,
Malcolm AJ
,
Wood KM
,
Cole M
,
Variend S
,
Cullinane C
,
Pearson ADJ
,
Lunec J
,
Tweddle DA
DOI
Quantitative assessment of mixed chimerism in allogeneic stem cell transplant patients: A comparison of molecular genetic and cytogenetic approaches
Journal of Pediatric Hematology/Oncology
2007; 29(6):428-431
Routledge D
,
Jackson A
,
Bourn D
,
Bown N
,
Cole M
,
Slatter MA
,
Gennery AR
,
Curtis A
DOI
Pharmacokinetics and metabolism of 13-cis-retinoic acid (isotretinoin) in children with high-risk neuroblastoma – A study of the United Kingdom Children's Cancer Study Group
British Journal of Cancer
2007; 96(3):424-431
Veal GJ
,
Cole M
,
Errington J
,
Pearson ADJ
,
Foot ABM
,
Whyman G
,
Boddy AV
DOI
Potential clinical impact of taking multiple blood samples for research studies in paediatric oncology: How much do we really know?
Pediatric Blood & Cancer
2006; 46(7):723-727
Cole M
,
Boddy AV
,
Kearns P
,
Teh KH
,
Price L
,
Parry A
,
Pearson ADJ
,
Veal GJ
DOI
A study to determine the minimum volume of blood necessary to be discarded from a central venous catheter before a valid sample is obtained in children with cancer
Pediatric Blood & Cancer
2007; 48(7):687-695
Cole M
,
Price L
,
Parry A
,
Picton S
,
Waters F
,
Marshall S
,
Goran C
,
Parnham A
,
Wastell H
,
Reid MM
,
Pearson ADJ
,
Boddy AV
,
Veal GJ
DOI
Pharmacokinetics of dactinomycin in a pediatric patient population: A United Kingdom Children's Cancer Study Group Study
Clinical Cancer Research
2005; 11(16):5893-5899
Veal GJ
,
Cole M
,
Errington J
,
Parry A
,
Hale J
,
Pearson ADJ
,
Howe K
,
Chisholm JC
,
Beane C
,
Brennan B
,
Waters F
,
Glaser A
,
Hemsworth S
,
McDowell H
,
Wright Y
,
Pritchard-Jones K
,
Pinkerton R
,
Jenner G
,
Nicholson J
,
Elsworth AM
,
Boddy AV
DOI
Estimation of glomerular filtration rate in paediatric cancer patients using 51CR-EDTA population pharmacokinetics
British Journal of Cancer
2004; 90(1):60–64
Cole M
,
Price L
,
Parry A
,
Keir MJ
,
Pearson ADJ
,
Boddy AV
,
Veal GJ
DOI
Randomized cross-over clinical trial to study potential pharmacokinetic interactions between cisplatin or carboplatin and etoposide
British Journal of Clinical Pharmacology
2002; 53(1):83-91
Thomas HD
,
Porter DJ
,
Bartelink I
,
Nobbs JR
,
Cole M
,
Elliott S
,
Newell DR
,
Calvert AH
,
Highley M
,
Boddy AV
DOI
The molecular pathology of p53 in primitive neuroectodermal tumours of the central nervous system
British Journal of Cancer
2002; 86(7):1117-1123
Burns ASYW
,
Jaros E
,
Cole M
,
Perry R
,
Pearson AJ
,
Lunec J
DOI
Cyclophosphamide metabolism in children following a 1-h and a 24-h infusion
Cancer Chemotherapy and Pharmacology
2001; 47(3):222-228
Yule SM
,
Price L
,
Cole M
,
Pearson AD
,
Boddy AV
DOI
A demographic study of the clinical significance of minimal residual disease in children with acute lymphoblastic leukemia
Medical and Pediatric Oncology
2001; 36(3):365-371
Levett D
,
Middleton P
,
Cole M
,
Reid MM
DOI
Cyclophosphamide metabolism in children with Fanconi's anaemia
Bone Marrow Transplantation
1999; 24(2):123-128
Yule SM
,
Price L
,
Cole M
,
Pearson AD
,
Boddy AV
DOI
The effect of fluconazole on cyclophosphamide metabolism in children
Drug Metabolism and Disposition
1999; 27(3):417-421
Yule SM
,
Walker D
,
Cole M
,
McSorley L
,
Cholerton S
,
Daly AK
,
Pearson ADJ
,
Boddy AV
A study of the feasibility and accuracy of pharmacokinetically guided etoposide dosing in children
British Journal of Cancer
1998; 77(12):2318-2323
Lowis SP
,
Price L
,
Pearson AD
,
Newell DR
,
Cole M
DOI
Neonatal vitamin K administration and childhood cancer in the north of England: Retrospective case-control study
BMJ
1998; 316(7126):189-193
Parker L
,
Cole M
,
Craft AW
,
Hey EN
DOI
Cyclophosphamide pharmacokinetics in children
British Journal of Clinical Pharmacology
1996; 41(1):13-19
Yule SM
,
Boddy AV
,
Cole M
,
Price L
,
Wyllie R
,
Tasso MJ
,
Pearson ADJ
,
Idle JR
DOI
Comparison of methods for the estimation of carboplatin pharmacokinetics in paediatric cancer patients
European Journal of Cancer
1995; 31(11):1804-1810
Peng B
,
Boddy AV
,
Cole M
,
Pearson ADJ
,
Chatelut E
,
Rubie H
,
Newell DR
DOI
Urinary creatinine adjusted reference ranges for homovanillic and vanillylmandelic acid in children and adults
Clinica Chimica Acta
1995; 236(1):19-32
Cole M
,
Craft AW
,
Parker L
,
Bell S
,
Seviour JA
,
McGill AC
,
Dale G
DOI
Screening for wilms' tumour in patients with aniridia, Beckwith syndrome, or hemihypertrophy
Medical and Pediatric Oncology
1995; 224(4):231-234
Craft AW
,
Parker L
,
Stiller C
,
Cole M
DOI
The kinetics of the auto-induction of ifosfamide metabolism during continuous infusion
Cancer Chemotherapy and Pharmacology
1995; 36(1):53-60
Boddy AV
,
Cole M
,
Pearson AD
,
Idle JR
DOI
Expression of µ Class Glutathione S-Transferase Correlates with Event-free Survival in Childhood Acute Lymphoblastic Leukemia
Cancer Research
1994; 54(20):5251-5254
Hall AG
,
Autzen P
,
Cattan AR
,
Malcolm AJ
,
Cole M
,
Kernahan J
,
Reid MM
Screening infants for neuroblastoma: The parents' perspective in false-positive cases
Pediatric Hematology and Oncology
1994; 11(2):157-163
Bell S
,
Parker L
,
Cole M
,
Craft AW
DOI
Inaccuracy of glomerular filtration rate estimation from height/plasma creatinine ratio
Archives of Disease in Childhood
1994; 70(5):387-390
Skinner R
,
Cole M
,
Pearson AD
,
Keir MJ
,
Price L
,
Wyllie RA
,
Coulthard MG
,
Craft AW
DOI
False positive results in a neuroblastoma screening programme
Medical and Pediatric Oncology
1994; 22(3):181-186
Bell S
,
Parker L
,
Craft AW
,
Dale G
,
McGill AC
,
Seviour J
,
Cole M
,
Smith J
DOI
Etoposide pharmacokinetics in children: The development and prospective validation of a dosing equation
Cancer Res
1993; 53(20):4881-4889
Lowis SP
,
Pearson ADJ
,
Newell DR
,
Cole M
Creatinine related reference ranges for urinary homovanillic acid and vanillylmandelic acid at 6 months of age
Archives of Disease in Childhood
1993; 68(3):376–378
Cole M
,
Parker L
,
Craft AW
,
Bell S
,
Dale G
,
McGill AC
,
Seviour JA
,
Smith J
DOI
Screening for neuroblastoma in the north of England
BMJ
1992; 3055(6864):1260-1263
Parker L
,
Craft AW
,
Dale G
,
Bell S
,
Cole M
,
McGill AC
,
Seviour JA
,
Smith J
DOI
A pilot study of screening for neuroblastoma in the north of England
Journal of Pediatric Hematology/Oncology
1992; 14(4):337-341
Craft AW
,
Parker L
,
Dale G
,
McGill AC
,
Seviour JA
,
Bell S
,
Cole M
,
Smith J
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