Biography
Background
I am a statistician with interests in methods for improving the design and analysis of clinical trials. As well as working in methodology development I have a great interest in collaborating on real trials to apply new methods in practice.
I have been at Newcastle University since July 2017.
Areas of expertise
- Biostatistics
- Clinical trials
- Novel trial design
Research
My research focuses on statistical methods for improved design and analysis of clinical trials. I am particularly interested in:
- Adaptive designs for clinical trials;
- Methods for incorporating biomarkers into clinical trials to stratify patients by treatment response;
- Improved methods for analysing composite endpoints, in particular ones with continuous components.
Scopus: Click here
Contact
- Email: james.wason@ncl.ac.uk
- Telephone: +44 (0) 191 208 3699
- Address: Population Health Sciences Institute, 4th Floor Ridley Building 1, Queen Victoria Road, Newcastle upon Tyne NE1 7RU, UK
FAQs
Q: How do you pronounce your surname?
A: It rhymes with Mason, like ‘Way-son’.
Publications
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(2023).
Online Multiple Hypothesis Testing.
Statistical Science.
(2023).
A Comparison of Randomization Methods for Multi-Arm Clinical Trials.
Statistics in Biopharmaceutical Research.
(2023).
The potential of innovative trial design for efficiently evaluating repurposed drugs.
Nature Reviews Drug Discovery.
(2023).
Current practices in studies applying the target trial emulation framework: a protocol for a systematic review.
BMJ Open.
(2023).
Bayesian borrowing for basket trials with longitudinal outcomes.
Statistics in Medicine.
(2023).
A randomised study of rituximab and belimumab sequential therapy in PR3 ANCA-associated vasculitis (COMBIVAS): design of the study protocol.
Trials.
(2023).
A novel nano-iron supplement versus standard treatment for iron deficiency anaemia in children 6–35 months (IHAT-GUT trial): a double-blind, randomised, placebo-controlled non-inferiority phase II trial in The Gambia.
eClinicalMedicine.
(2022).
Point estimation following a two-stage group sequential trial.
Statistical Methods in Medical Research.
(2022).
Bayesian modelling strategies for borrowing of information in randomised basket trials.
Journal of the Royal Statistical Society: Series C (Applied Statistics).
(2022).
Design and analysis of umbrella trials: Where do we stand?.
Frontiers in Medicine.
(2022).
Subgroup analyses in randomized controlled trials frequently categorized continuous subgroup information.
Journal of Clinical Epidemiology.
(2022).
A hybrid approach to comparing parallel-group and stepped-wedge cluster-randomized trials with a continuous primary outcome when there is uncertainty in the intra-cluster correlation.
Clinical Trials.
(2022).
Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls.
Gastroenterology.
(2022).
Bayesian sample size determination in basket trials borrowing information between subsets.
Biostatistics.
(2022).
Bayesian sample size determination in basket trials borrowing information between subsets.
Biostatistics.
(2022).
Practical guidance for planning resources required to support publicly-funded adaptive clinical trials.
BMC Medicine.