The WIRE study a phase II, multi-arm, multi-centre, non-randomised window-of-opportunity clinical trial platform using a Bayesian adaptive design for proof-of-mechanism of novel treatment strategies in operable renal cell cancer – a study protocol
Stephan Ursprung,
Helen Mossop,
Ferdia A. Gallagher,
Evis Sala,
Richard Skells,
Jamal A. N. Sipple,
Thomas J. Mitchell,
Anita Chhabra,
Kate Fife,
Athena Matakidou,
Gemma Young,
Amanda Walker,
Martin G. Thomas,
Mireia Crispin Ortuzar,
Mark Sullivan,
Andrew Protheroe,
Grenville Oades,
Balaji Venugopal,
Anne Y. Warren,
John Stone,
Tim Eisen,
James Wason,
Sarah J. Welsh,
Grant D. Stewart November 2021