Publications

(2022). Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls. Gastroenterology.

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(2020). Bayesian bandit models for the design of clinical trials. PhD Thesis, Lancaster University 2020; DOI:10.17635/lancaster/thesis/917.

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(2019). Design of Multi-Arm, Multi-Stage Trials in Oncology. In Textbook of Clinical Trials in Oncology: A Statistical Perspective.

(2019). Shared heritability and functional enrichment across six solid cancers. Nat Commun 2019; 10:431.

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(2018). Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nat Genet 2018; 50:1412–25.

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(2017). Novel blood pressure locus and gene discovery using genome-wide association study and expression data sets from blood and the kidney. Hypertension 2017; 70:e4-19.

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(2017). What is an ROC curve?. Emerg Med J 2017; 34:357-9.

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(2016). Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Nature Genet 2016; 48:1462-72.

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(2016). Anticoagulation in haemodialysis in children: A thirty-period crossover trial. In Aston P et al (eds) UK Success Stories in Industrial Mathematics. Springer, Cham.

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(2015). Multi-Arm Multi-Stage Designs for Clinical Trials with Treatment Selection. In Modern Adaptive Randomized Clinical Trials: Statistical and Practical Aspects.

(2014). Recent Developments in Group-Sequential Designs. In Developments in Statistical Evaluation of Clinical Trials 2014; 97-118.

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(2014). Surgical treatment of stage IA2 cervical cancer. Cochrane Database Syst Rev 2014; 5:CD010870.

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(2013). SNPedia. Encyclopedia of Systems Biology.

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(2013). Disease Databases. Encyclopedia of Systems Biology.

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(2013). Cancer Resources. Encyclopedia of Systems Biology.

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(2011). Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 2011; 476:214-9.

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(2011). Chemoradiation for advanced primary vulval cancer. Cochrane Database Syst Rev 2011; 4:CD003752.

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(2008). Introduction: ENBIS, pro-ENBIS and this book. In Coleman S et al (eds), Statistical Practice in Business and Industry.

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(2007). Six sigma training programmes to help SMEs improve. Intelligent Production Machines and Systems 2006; 2nd I*PROMS Virtual International Conference 3–14 July 2006:39-44.

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(2005). Genetic linkage studies. The Lancet 366:P1036-44.

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(1994). Multi-period crossover trials. Stat Meth Med Res 1994; 3:383-405.

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