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Isabella Harumi Yonehara Noma
,
Larissa Anastacio da Costa Carvalho
,
Denisse Esther Mallaupoma Camarena
,
Renaira Oliveira Silva
,
Manoel Oliveira de Moraes Junior
,
Sophia Tavares de Souza
,
Julia Newton-Bishop
,
Jérémie Nsengimana
,
Silvya Stuchi Maria-Engler
(2024).
Peroxiredoxin-2 represses NRAS-mutated melanoma cells invasion by modulating EMT markers
.
Biomedicine & Pharmacotherapy
.
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DOI
URL
Faye Wolstenhulme
,
Irena Bibby
,
Michael Cole
,
Lydia Grixti
,
Naomi McGregor
,
Penny Bradley
,
Rebecca H Maier
,
Jenn Walker
,
Simon H Pearce
,
James Wason
(2024).
Graves-PCD: protocol for a randomised, dose-finding, adaptive trial of the plasma cell-depleting agent daratumumab in severe Graves’ disease
.
BMJ Open
.
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DOI
URL
Karen Schreiber
,
Christine Graversgaard
,
Beverley J Hunt
,
James M S Wason
,
Nathalie Costedoat-Chalumeau
,
Silvia Aguilera
,
Marta M Guerra
,
Jane E Salmon
(2024).
Challenges of designing and conducting cohort studies and clinical trials in populations of pregnant people
.
The Lancet Rheumatology
.
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DOI
URL
Athimalaipet V Ramanan
,
James M S Wason
(2024).
Adaptive and innovative study design in rare diseases
.
Archives of Disease in Childhood
.
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DOI
URL
Andrew J Fisher
,
Michael White
,
Nicola Goudie
,
Anneka Kershaw
,
Julia Phillipson
,
Michelle Bardgett
,
Joanne Lally
,
Alex Bevin-Nicholls
,
Thomas Chadwick
,
Andrew Bryant
,
Sian Russell
,
Hesther Smith
,
Laura Frisby
,
Rebecca Errington
,
Martin Carby
,
Richard Thompson
,
Karthik Santhanakrishnan
,
Jasvir Parmar
,
James L Lordan
,
Luke Vale
,
Helen Hancock
,
Catherine Exley
,
Andrew R Gennery
,
James MS Wason
(2024).
Extracorporeal photopheresis (ECP) in the treatment of chronic lung allograft dysfunction (CLAD): a prospective, multicentre, open-label, randomised controlled trial studying the addition of ECP to standard care in the treatment of bilateral lung transplant patients with CLAD (E-CLAD UK)
.
BMJ Open Respiratory Research
.
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DOI
URL
Karen Yirmiya
,
Matthew Constantinou
,
Elizabeth Simes
,
Anthony Bateman
,
James Wason
,
Jessica Yakeley
,
Mary McMurran
,
Mike Crawford
,
Alison Frater
,
Paul Moran
,
Barbara Barrett
,
Angus Cameron
,
Zoe Hoare
,
Elizabeth Allison
,
Stephen Pilling
,
Stephen Butler
,
Peter Fonagy
(2024).
The mediating role of reflective functioning and general psychopathology in the relationship between childhood conduct disorder and adult aggression among offenders
.
Psychological Medicine
.
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DOI
URL
Leher Gumber
,
Opeyemi Agbeleye
,
Alex Inskip
,
Ross Fairbairn
,
Madeleine Still
,
Luke Ouma
,
Jingky Lozano-kuehne
,
Michelle Bardgett
,
John D Isaacs
,
James MS Wason
,
Dawn Craig
,
Arthur G Pratt
(2024).
Operational complexities in international clinical trials: a systematic review of challenges and proposed solutions
.
BMJ Open
.
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DOI
URL
Lucy Godson
,
Navid Alemi
,
Jérémie Nsengimana
,
Graham P. Cook
,
Emily L. Clarke
,
Darren Treanor
,
D. Timothy Bishop
,
Julia Newton-Bishop
,
Ali Gooya
,
Derek Magee
(2024).
Immune subtyping of melanoma whole slide images using multiple instance learning
.
Medical Image Analysis
.
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DOI
URL
Nicola J Wyatt
,
Hannah Watson
,
Carl A Anderson
,
Nicholas A Kennedy
,
Tim Raine
,
Tariq Ahmad
,
Dean Allerton
,
Michelle Bardgett
,
Emma Clark
,
Dawn Clewes
,
Cristina Cotobal Martin
,
Mary Doona
,
Jennifer A Doyle
,
Katherine Frith
,
Helen C Hancock
,
Ailsa L Hart
,
Victoria Hildreth
,
Peter M Irving
,
Sameena Iqbal
,
Ciara Kennedy
,
Andrew King
,
Sarah Lawrence
,
Charlie W Lees
,
Robert Lees
,
Laura Letchford
,
Trevor Liddle
,
James O Lindsay
,
Rebecca H Maier
,
John C Mansfield
,
Julian R Marchesi
,
Naomi McGregor
,
Rebecca E McIntyre
,
Jasmin Ostermayer
,
Tolulope Osunnuyi
,
Nick Powell
,
Natalie J Prescott
,
Jack Satsangi
,
Shriya Sharma
,
Tara Shrestha
,
Ally Speight
,
Michelle Strickland
,
James MS Wason
,
Kevin Whelan
,
Ruth Wood
,
Gregory R Young
,
Xinyue Zhang
,
Miles Parkes
,
Christopher J Stewart
,
Luke Jostins-Dean
,
Christopher A Lamb
(2024).
Defining predictors of responsiveness to advanced therapies in Crohn’s disease and ulcerative colitis: protocol for the IBD-RESPONSE and nested CD-metaRESPONSE prospective, multicentre, observational cohort study in precision medicine
.
BMJ Open
.
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DOI
URL
William King
,
Tara Homer
,
Chris Harding
,
Helen Mossop
,
Thomas Chadwick
,
Alaa Abouhajar
,
Luke Vale
(2024).
Cost-effectiveness of methenamine hippurate compared with antibiotic prophylaxis for the management of recurrent urinary tract infections in secondary care: a multicentre, open-label, randomised, non-inferiority trial
.
BMJ Open
.
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DOI
URL
Suraiya Dubash
,
Tara D. Barwick
,
Kasia Kozlowski
,
Andrea G. Rockall
,
Sairah Khan
,
Sameer Khan
,
Siraj Yusuf
,
Angela Lamarca
,
Juan W. Valle
,
Richard A. Hubner
,
Mairéad G. McNamara
,
Andrea Frilling
,
Tricia Tan
,
Florian Wernig
,
Jeannie Todd
,
Karim Meeran
,
Bhavesh Pratap
,
Saleem Azeem
,
Michael Huiban
,
Nicholas Keat
,
Jingky P. Lozano-Kuehne
,
Eric O. Aboagye
,
Rohini Sharma
(2024).
Somatostatin Receptor Imaging with [18F]FET-βAG-TOCA PET/CT and [68Ga]Ga-DOTA-Peptide PET/CT in Patients with Neuroendocrine Tumors: A Prospective, Phase 2 Comparative Study
.
Journal of Nuclear Medicine
.
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DOI
URL
Frances Varian
,
Jennifer Dick
,
Christian Battersby
,
Stefan Roman
,
Jenna Ablott
,
Lisa Watson
,
Sarah Binmahfooz
,
Hamza Zafar
,
Gerry Colgan
,
John Cannon
,
Jay Suntharalingam
,
Jim Lordan
,
Luke Howard
,
Colm McCabe
,
John Wort
,
Laura Price
,
Colin Church
,
Neil Hamilton
,
Iain Armstrong
,
Abdul Hameed
,
Judith Hurdman
,
Charlie Elliot
,
Robin Condliffe
,
Martin Wilkins
,
Alastair Webb
,
David Adlam
,
Ray L. Benza
,
Kazem Rahimi
,
Mohadeseh Shojaei‐Shahrokhabadi
,
Nan X. Lin
,
James M. S. Wason
,
Alasdair McIntosh
,
Alex McConnachie
,
Jennifer T. Middleton
,
Roger Thompson
,
David G. Kiely
,
Mark Toshner
,
Alexander Rothman
(2024).
Pulmonary Hypertension: Intensification and Personalization of Combination Rx (PHoenix): A phase IV randomized trial for the evaluation of dose‐response and clinical efficacy of riociguat and selexipag using implanted technologies
.
Pulmonary Circulation
.
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DOI
URL
Shaun Hiu
,
Tingting Yong
,
Jahfer Hasoon
,
M. Dawn Teare
,
John‐Paul Taylor
,
Nan Lin
(2024).
Instrumental variables in real‐world clinical studies of dementia and neurodegenerative disease: Systematic review of the subject‐matter argumentation, falsification test, and study design strategies to justify a valid instrument
.
Brain and Behavior
.
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DOI
URL
Heather Lambert
,
Shaun Hiu
,
Malcolm Coulthard
,
John N S Matthews
,
Ruth Wood
,
Jean Crosier
,
Rachel Agbeko
,
Thomas Brick
,
Heather Duncan
,
David Grant
,
Quen Mok
,
Andrew Gustaf Nyman
,
John Pappachan
,
Paul Wellman
,
Chris Boucher
,
Joe Bulmer
,
Denise Chisholm
,
Kirsten Cromie
,
Victoria Emmet
,
Richard Feltbower
,
Michael Grayling
,
Rebecca Harrison
,
Eva-Maria Holstein
,
Ciara A Kennedy
,
Elaine McColl
,
Kevin Morris
,
Lee Norman
,
Julie Office
,
Roger Parslow
,
Christine Pattinson
,
Shriya Sharma
,
Jonathan Smith
,
Alison Steel
,
Rachel Steel
,
Jayne Straker
,
Lamprini Vrana
,
Jenn Walker
,
Mike Whitaker
,
Jim Wightman
,
Nina Wilson
,
Lucy Wirz
(2024).
Evaluation of efficacy, outcomes and safety of infant haemodialysis and ultrafiltration in clinical use: I-KID a stepped wedge cluster RCT
.
Efficacy and Mechanism Evaluation
.
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DOI
URL
Svetlana Cherlin
,
Theophile Bigirumurame
,
Michael J Grayling
,
Jérémie Nsengimana
,
Luke Ouma
,
Aida Santaolalla
,
Fang Wan
,
S Faye Williamson
,
James MS Wason
(2023).
Utilising high-dimensional data in randomised clinical trials: A review of methods and practice
.
Research Methods in Medicine & Health Sciences
.
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DOI
URL
Janet A Wilson
,
Tony Fouweather
,
Deborah D Stocken
,
Tara Homer
,
Catherine Haighton
,
Nikki Rousseau
,
James O’Hara
,
Luke Vale
,
Rebecca Wilson
,
Sonya Carnell
,
Scott Wilkes
,
Jill Morrison
,
Kim Ah-See
,
Sean Carrie
,
Claire Hopkins
,
Nicola Howe
,
Musheer Hussain
,
Lyndsay Lindley
,
Kenneth MacKenzie
,
Lorraine McSweeney
,
Hisham Mehanna
,
Christopher Raine
,
Ruby Smith Whelan
,
Frank Sullivan
,
Alexander von Wilamowitz-Moellendorff
,
Dawn Teare
(2023).
Tonsillectomy compared with conservative management in patients over 16 years with recurrent sore throat: the NATTINA RCT and economic evaluation
.
Health Technology Assessment
.
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DOI
URL
Raya Vinogradov
,
Vikki Smith
,
Shaun Hiu
,
Catherine McParlin
,
Allison Farnworth
,
Vera Araújo-Soares
(2023).
Let’s talk aspirin: A survey of barriers and facilitators faced by midwives when engaging in conversations about aspirin with women at risk of pre-eclampsia
.
Midwifery
.
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DOI
URL
Ruth McGovern
,
Deborah Smart
,
Hayley Alderson
,
Tony Fouweather
,
Eileen Kaner
(2023).
Promoting Alcohol Reduction in Non-Treatment Seeking parents (PAReNTS): a pilot feasibility cluster randomized controlled trial of brief alcohol interventions with parents in contact with child safeguarding services
.
Alcohol and Alcoholism
.
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DOI
URL
David S. Robertson
,
James M. S. Wason
,
Aaditya Ramdas
(2023).
Online Multiple Hypothesis Testing
.
Statistical Science
.
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DOI
URL
Martin Law
,
Dominique-Laurent Couturier
,
Babak Choodari-Oskooei
,
Phillip Crout
,
Carrol Gamble
,
Peter Jacko
,
Philip Pallmann
,
Mark Pilling
,
David S. Robertson
,
Michael Robling
,
Matthew R. Sydes
,
Sofía S. Villar
,
James Wason
,
Graham Wheeler
,
S. Faye Williamson
,
Christina Yap
,
Thomas Jaki
(2023).
Medicines and Healthcare products Regulatory Agency’s “Consultation on proposals for legislative changes for clinical trials”: a response from the Trials Methodology Research Partnership Adaptive Designs Working Group, with a focus on data sharing
.
Trials
.
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DOI
URL
Sean Carrie
,
James O’Hara
,
Tony Fouweather
,
Tara Homer
,
Nikki Rousseau
,
Leila Rooshenas
,
Alison Bray
,
Deborah D Stocken
,
Laura Ternent
,
Katherine Rennie
,
Emma Clark
,
Nichola Waugh
,
Alison J Steel
,
Jemima Dooley
,
Michael Drinnan
,
David Hamilton
,
Kelly Lloyd
,
Yemi Oluboyede
,
Caroline Wilson
,
Quentin Gardiner
,
Naveed Kara
,
Sadie Khwaja
,
Samuel C Leong
,
Sangeeta Maini
,
Jillian Morrison
,
Paul Nix
,
Janet A Wilson
,
M Dawn Teare
(2023).
Clinical effectiveness of septoplasty versus medical management for nasal airways obstruction: multicentre, open label, randomised controlled trial
.
BMJ
.
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DOI
URL
Vicky Brocklebank
,
Patrick R. Walsh
,
Kate Smith-Jackson
,
Thomas M. Hallam
,
Kevin J. Marchbank
,
Valerie Wilson
,
Theophile Bigirumurame
,
Tina Dutt
,
Emma K. Montgomery
,
Michal Malina
,
Edwin K. S. Wong
,
Sally Johnson
,
Neil S. Sheerin
,
David Kavanagh
(2023).
Atypical hemolytic uremic syndrome in the era of terminal complement inhibition: an observational cohort study
.
Blood
.
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DOI
URL
Lindsay Pennington
,
Stuart Cunningham
,
Shaun Hiu
,
Ghada Khattab
,
Vicky Ryan
(2023).
The impact of the Speech Systems Approach on intelligibility for children with cerebral palsy: a secondary analysis
.
Efficacy and Mechanism Evaluation
.
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DOI
URL
Marjan Nouri-Keshtkar
,
Mohadeseh Shojaei Shahrokhabadi
,
Azadeh Ghaheri
,
Roya Hosseini
,
Hassan Ketabi
,
Mojtaba Farjam
,
Ding-Geng Chen
,
Mehdi Rezaeian
,
Reza Homayounfar
,
Yaser Tahamtani
,
Mehdi Totonchi
(2023).
Role of gender in explaining metabolic syndrome risk factors in an Iranian rural population using structural equation modelling
.
Scientific Reports
.
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DOI
URL
James M. S. Wason
,
Oliver Bandmann
(2023).
The potential of innovative trial design for efficiently evaluating repurposed drugs
.
Nature Reviews Drug Discovery
.
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DOI
URL
Mohita Tagore
,
Emiliano Hergenreder
,
Sarah C. Perlee
,
Nelly M. Cruz
,
Laura Menocal
,
Shruthy Suresh
,
Eric Chan
,
Maayan Baron
,
Stephanie Melendez
,
Asim Dave
,
Walid K. Chatila
,
Jérémie Nsengimana
,
Richard P. Koche
,
Travis J. Hollmann
,
Trey Ideker
,
Lorenz Studer
,
Andrea Schietinger
,
Richard M. White
(2023).
GABA Regulates Electrical Activity and Tumor Initiation in Melanoma
.
Cancer Discovery
.
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DOI
URL
Miranda Morton
,
Nina Wilson
,
Tara Marie Homer
,
Laura Simms
,
Alison Steel
,
Rebecca Maier
,
James Wason
,
Laura Ternent
,
Alaa Abouhajar
,
Maria Allen
,
Richard Joyce
,
Victoria Hildreth
,
Rachel Lakey
,
Svetlana Cherlin
,
Adam Walker
,
Graham Devereux
,
James D Chalmers
,
Adam T Hill
,
Charles Haworth
,
John R Hurst
,
Anthony De Soyza
(2023).
Dual bronchodilators in Bronchiectasis study (DIBS): protocol for a pragmatic, multicentre, placebo-controlled, three-arm, double-blinded, randomised controlled trial studying bronchodilators in preventing exacerbations of bronchiectasis
.
BMJ Open
.
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DOI
URL
Ruqayya A. Azher
,
James M. S. Wason
,
Michael J. Grayling
(2023).
A Comparison of Randomization Methods for Multi-Arm Clinical Trials
.
Statistics in Biopharmaceutical Research
.
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DOI
URL
Paula Cunnea
,
Edward W. Curry
,
Elizabeth L. Christie
,
Katherine Nixon
,
Chun Hei Kwok
,
Ahwan Pandey
,
Ratri Wulandari
,
Kerstin Thol
,
Jennifer Ploski
,
Cristina Morera-Albert
,
Stephen McQuaid
,
Jingky Lozano-kuehne
,
James J. Clark
,
Jonathan Krell
,
Euan A. Stronach
,
Iain A. McNeish
,
David D.L. Bowtell
,
Christina Fotopoulou
(2023).
Spatial and temporal intra-tumoral heterogeneity in advanced HGSOC: Implications for surgical and clinical outcomes
.
Cell Reports Medicine
.
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DOI
URL
Mark Lythgoe
,
Paola Dama
,
Adam Enver Frampton
,
Emily Pickford
,
Laura Tookman
,
Paula Cunnea
,
Christina Fotopoulou
,
Daniel Liu
,
James Clark
,
Jingky Lozano-kuehne
,
Philip David Badman
,
Aaron Clarke
,
Sasha Chetal
,
Gayle Fyvie
,
Alex Stevenson
,
Jonathan Krell
(2023).
Immune modulation and the oral live biotherapeutic product, MRx0518, in treatment-naïve patients with cancer: Updated safety data.
.
Journal of Clinical Oncology
.
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DOI
URL
Theophile Bigirumurame
,
Shaun Kuan Wei Hiu
,
M Dawn Teare
,
James M S Wason
,
Andrew Bryant
,
Matthew Breckons
(2023).
Current practices in studies applying the target trial emulation framework: a protocol for a systematic review
.
BMJ Open
.
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DOI
URL
Janet A Wilson
,
James O’Hara
,
Tony Fouweather
,
Tara Homer
,
Deborah D Stocken
,
Luke Vale
,
Catherine Haighton
,
Nikki Rousseau
,
Rebecca Wilson
,
Lorraine McSweeney
,
Scott Wilkes
,
Jill Morrison
,
Kenneth MacKenzie
,
Kim Ah-See
,
Sean Carrie
,
Claire Hopkins
,
Nicola Howe
,
Musheer Hussain
,
Hisham Mehanna
,
Christopher Raine
,
Frank Sullivan
,
Alexander von Wilamowitz-Moellendorff
,
M Dawn Teare
(2023).
Conservative management versus tonsillectomy in adults with recurrent acute tonsillitis in the UK (NATTINA): a multicentre, open-label, randomised controlled trial
.
The Lancet
.
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DOI
URL
Lou E. Whitehead
,
Oliver Sailer
,
Miles D. Witham
,
James M. S. Wason
(2023).
Bayesian borrowing for basket trials with longitudinal outcomes
.
Statistics in Medicine
.
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DOI
URL
Heather Lambert
,
Shaun Hiu
,
Malcolm G. Coulthard
,
John N. S. Matthews
,
Eva-Maria Holstein
,
Jean Crosier
,
Rachel Agbeko
,
Thomas Brick
,
Heather Duncan
,
David Grant
,
Quen Mok
,
Andrew Gustaf Nyman
,
John Pappachan
,
Chris Boucher
,
Joe Bulmer
,
Denise Chisholm
,
Kirsten Cromie
,
Victoria Emmet
,
Richard G. Feltbower
,
Arunoday Ghose
,
Michael Grayling
,
Rebecca Harrison
,
Ciara A. Kennedy
,
Elaine McColl
,
Kevin Morris
,
Lee Norman
,
Julie Office
,
Roger Parslow
,
Christine Pattinson
,
Shriya Sharma
,
Jonathan Smith
,
Alison Steel
,
Rachel Steel
,
Jayne Straker
,
Lamprini Vrana
,
Jenn Walker
,
Paul Wellman
,
Mike Whitaker
,
Jim Wightman
,
Nina Wilson
,
Lucy Wirz
,
Ruth Wood
(2023).
The Infant KIdney Dialysis and Utrafiltration (I-KID) Study: A Stepped-Wedge Cluster-Randomized Study in Infants, Comparing Peritoneal Dialysis, Continuous Venovenous Hemofiltration, and Newcastle Infant Dialysis Ultrafiltration System, a Novel Infant Hemodialysis Device
.
Pediatric Critical Care Medicine
.
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DOI
URL
Barry Wright
,
Ellen Kingsley
,
Cindy Cooper
,
Katie Biggs
,
Matthew Bursnall
,
Han-I Wang
,
Tim Chater
,
Elizabeth Coates
,
M Dawn Teare
,
Kirsty McKendrick
,
Gina Gomez de la Cuesta
,
Amy Barr
,
Kiera Solaiman
,
Anna Packham
,
David Marshall
,
Danielle Varley
,
Roshanak Nekooi
,
Steve Parrott
,
Shehzad Ali
,
Simon Gilbody
,
Ann Le Couteur
(2023).
I-SOCIALISE: Results from a cluster randomised controlled trial investigating the social competence and isolation of children with autism taking part in LEGO® based therapy (‘Play Brick Therapy’) clubs in school environments
.
Autism
.
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DOI
URL
Mark E. McClure
,
Seerapani Gopaluni
,
James Wason
,
Robert B. Henderson
,
Andre Van Maurik
,
Caroline C.O. Savage
,
Charles D. Pusey
,
Alan D. Salama
,
Paul A. Lyons
,
Jacinta Lee
,
Kim Mynard
,
David R. Jayne
,
Rachel B. Jones
(2023).
A randomised study of rituximab and belimumab sequential therapy in PR3 ANCA-associated vasculitis (COMBIVAS): design of the study protocol
.
Trials
.
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DOI
URL
Henry David Jeffry Hogg
,
Katie Brittain
,
Dawn Teare
,
James Talks
,
Konstantinos Balaskas
,
Pearse Keane
,
Gregory Maniatopoulos
(2023).
Safety and efficacy of an artificial intelligence-enabled decision tool for treatment decisions in neovascular age-related macular degeneration and an exploration of clinical pathway integration and implementation: protocol for a multi-methods validation study
.
BMJ Open
.
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DOI
URL
Toshi A Furukawa
,
Aran Tajika
,
Masatsugu Sakata
,
Yan Luo
,
Rie Toyomoto
,
Masaru Horikoshi
,
Tatsuo Akechi
,
Norito Kawakami
,
Takeo Nakayama
,
Naoki Kondo
,
Shingo Fukuma
,
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