2

Antiplatelet therapy in the primary prevention of cardiovascular disease in patients with chronic obstructive pulmonary disease: Protocol of a randomised controlled proof-of-concept trial (APPLE COPD-ICON 2)

*BMJ Open* 2018; 8(5):e020713

Improving the analysis of composite endpoints in rare disease trials

*Orphanet Journal of Rare Diseases* 2018; 13:81

Continuous low-dose antibiotic prophylaxis to prevent urinary tract infection in adults who perform clean intermittent self-catheterisation: The AnTIC RCT

*Health Technology Assessment* 2018; 22(24)

The impact of autoimmune hepatitis and its treatment on health utility

*Hepatology* 2018; 68(4):1487-1497

β-Catenin–mediated immune evasion pathway frequently operates in primary cutaneous melanomas

*Journal of Clinical Investigation* 2018; 128(5):2048-2063

An optimised multi-arm multi-stage clinical trial design for unknown variance

*Contemporary Clinical Trials* 2018; 67:116-120

Drooling Reduction Intervention randomised trial (DRI): Comparing the efficacy and acceptability of hyoscine patches and glycopyrronium liquid on drooling in children with neurodisability

*Archives of Disease in Childhood* 2018; 103(4):371-376

Gastrostomy versus nasogastric tube feeding for chemoradiation patients with head and neck cancer: The TUBE pilot RCT

*Health Technology Assessment* 2018; 22(16)

Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population

*Carcinogenesis* 2018; 39(3):336-346

Response‐adaptive designs for binary responses: How to offer patient benefit while being robust to time trends?

*Pharmaceutical Statistics* 2018; 17(2):182-197