2

Adaptive Designs: Benefits and Cautions for Neurosurgery Trials

Methenamine hippurate compared with antibiotic prophylaxis to prevent recurrent urinary tract infections in women: the ALTAR non-inferiority RCT

When is a two-stage single-arm trial efficient? An evaluation of the impact of outcome delay

Alternative to prophylactic antibiotics for the treatment of recurrent urinary tract infections in women: multicentre, open label, randomised, non-inferiority trial

Capturing the real-world benefit of residual $p̆beta$-cell function during clinically important time-periods in established Type 1 diabetes

Defining novel causal SNPs and linked phenotypes at melanoma-associated loci

Designing Multi-arm Multistage Adaptive Trials for Neuroprotection in Progressive Multiple Sclerosis

The role of comorbidities alongside patient and disease characteristics on long-term disease activity in RA using UK inception cohort data

Genes regulated by DNA methylation are involved in distinct phenotypes during melanoma progression and are prognostic factors for patients

Optimised point estimators for multi-stage single-arm phase II oncology trials