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James Wason

Professor of Biostatistics

Population Health Sciences Institute

Background

I am a statistician with interests in methods for improving the design and analysis of clinical trials. As well as working in methodology development I have a great interest in collaborating on real trials to apply new methods in practice.

I have been at Newcastle University since July 2017. I currently retain a part-time position in the MRC Biostatistics Unit, University of Cambridge.

Areas of expertise

  • Biostatistics
  • Clinical trials
  • Novel trial design

Research

My research focuses on statistical methods for improved design and analysis of clinical trials. I am particularly interested in:

  1. Adaptive designs for clinical trials;
  2. Methods for incorporating biomarkers into clinical trials to stratify patients by treatment response;
  3. Improved methods for analysing composite endpoints, in particular ones with continuous components.

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Publications

You can quickly discover relevant content by members of the PHSI-BRG by filtering publications here.

Design of experiments for a confirmatory trial of precision medicine

Journal of Statistical Planning and Inference 2019; 199:179-187

Design of telehealth trials – Introducing adaptive approaches

International Journal of Medical Informatics 2014; 83(12):870-880

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Nature 2011; 476(7359):214-219