The methodology group develops, disseminates, and implements new statistical methods to improve the efficiency of clinical trials.

Current areas of research

  • Adaptive designs.
  • Basket and umbrella trials.
  • Bayesian methods.
  • Cluster-randomised and stepped-wedge trials.
  • Composite endpoints.
  • Crossover trial designs.
  • Early phase oncology trials.
  • Multi-arm multi-stage (MAMS) trials.
  • Observational study designs.
  • Pilot and feasibility studies.
  • Platform trials.
  • Trials of complex interventions.
  • Trials of proportionate interventions.
  • Using historical data.

If you are interested in discussing a study that may require novel methods, please contact Prof James Wason.