The methodology group develops, disseminates, and implements new statistical methods to improve the efficiency of clinical trials.

Current areas of research

  • Adaptive designs
  • Basket and umbrella trials
  • Bayesian methods
  • Cluster-randomised and stepped-wedge trials
  • Composite endpoints
  • Crossover trial designs
  • Early phase oncology trials
  • Multi-arm multi-stage (MAMS) trials
  • Observational study designs
  • Pilot and feasibility studies
  • Platform trials
  • Transforming IMID trials
  • Trials of complex interventions
  • Trials of proportionate interventions
  • Using historical data

If you are interested in discussing a study that may require novel methods, please contact Prof James Wason.


PhD students