Michael Grayling

Michael Grayling

Associate Researcher

Population Health Sciences Institute


I was a Newcastle University Research Fellow at Newcastle University from 2018 to 2022. Prior to this I was a statistician at the MRC Biostatistics Unit, University of Cambridge.

I am now a principal statistician at Janssen. I remain an associate researcher at Newcastle University and supervise a number of PhD students in the BRG.

I am interested in the design and analysis of clinical trials. My work has involved a mixture of developing novel statistical methodology for trials, comparing existing method performance, and collaborating on real trials. I also work on developing user-friendly software for trial design; I created and maintain the multiarm app for designing fixed-sample and adaptive (group-sequential/drop-the-losers) multi-arm trials, available here.

PhD students


  • Adaptive design
  • Early phase oncology trials
  • Crossover trials
  • Stepped-wedge trials
  • Wellcome Trust PhD Programme in Mathematical Genomics and Medicine, 2012-16

    MRC Biostatistics Unit, University of Cambridge

  • Systems Biology MSci, 2011-12

    University of Cambridge

  • Mathematics BA (Hons), 2008-11

    University of Cambridge