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Latest
Pulmonary Hypertension: Intensification and Personalization of Combination Rx (PHoenix): A phase IV randomized trial for the evaluation of dose‐response and clinical efficacy of riociguat and selexipag using implanted technologies
Online Multiple Hypothesis Testing
A Comparison of Randomization Methods for Multi-Arm Clinical Trials
The potential of innovative trial design for efficiently evaluating repurposed drugs
Bayesian borrowing for basket trials with longitudinal outcomes
Bayesian modelling strategies for borrowing of information in randomised basket trials
Design and analysis of umbrella trials: Where do we stand?
Subgroup analyses in randomized controlled trials frequently categorized continuous subgroup information
Practical guidance for planning resources required to support publicly-funded adaptive clinical trials
Adaptive Designs: Benefits and Cautions for Neurosurgery Trials
When is a two-stage single-arm trial efficient? An evaluation of the impact of outcome delay
Bayesian sample size determination using commensurate priors to leverage preexperimental data
Improving power in PSA response analyses of metastatic castration-resistant prostate cancer trials
Response adaptive intervention allocation in stepped-wedge cluster randomized trials
Advantages of multi-arm non-randomised sequentially allocated cohort designs for Phase II oncology trials
Costs and staffing resource requirements for adaptive clinical trials: quantitative and qualitative results from the Costing Adaptive Trials project
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